Is the Rattus norvegicus Population Playing a Role in the Transmission of Zoonotic Diseases to Children? A Pilot Study in Tehran, Iran

Background: Due to frequent exposure surface water and contact with animals, children represent a group susceptible zoonotic diseases. Objectives: The present study aims determine the presence prevalence of main agents in R. norvegicus populations Tehran, Iran. Methods: In study, 100 were captured within time span one year from five districts Fecal blood samples collected rodents serum was recovered after centrifugation. specific IgG antibodies against Leptospira spp. Rabies virus detected using commercial qualitative rat ELISA kit. A conventional PCR assay employed detect Vibrio vulnificus commensal population. Results: general, 80% (n = 80/100) 20% 20/100) rats males females, respectively. results ELSA showed that 7% 7/100) 1% 1/100) positive for virus, revealed highest frequency (20%; 4/20) among eastern part Tehran. only southern (5%; 1/20) Results method percentage tested V. 5%. Overall, surveyed microorganisms had 5/20; 25%) lowest 1/20; 5%) rates northern parts Conclusions: accentuate necessity implementing rodent control programs regular disinfection as well avoiding urban environments.